Retinal Lineage Therapeutic Specific Effect of Human Orbital and Abdominal Adipose-Derived Mesenchymal Stem Cells

Figure 5

Retinal layers 21 days post transplantation of ABASCs and OASCs in the NaIO3 mice model. (a) Immunohistochemistry pictures of mice retinas for ONL quantification and rhodopsin intensity by DAPI and rhodopsin staining in ABASCs and OASCs transplanted mice versus controls. Yellow arrows indicate the PR layer. (b) Immunohistochemistry pictures of the mice RPE layer after RPE65 and DAPI staining in ABASC and OASC transplanted mice versus controls. Yellow arrows indicate the RPE layer. (c) Graphic summary of RPE65 intensity evident by RPE65. (d) Graphic summary of rhodopsin intensity evident by rhodopsin staining. (e) Graphic summary of ONL thickness evident by DAPI staining. (f) Graphic summary of INL thickness evident by DAPI staining. ONL: outer nuclear layer; INL: inner nuclear layer; RGC: retinal ganglion layer; PR: photoreceptor; RPE: retinal pigment epithelium. . For each group of mice, . Data are represented as .