Research Article

Characterization and miRNA Profiling of Extracellular Vesicles from Human Osteoarthritic Subchondral Bone Multipotential Stromal Cells (MSCs)

Figure 1

OA-MSC-EV characterization. (a) Flow cytometry of CD63, CD9, and CD81 surface markers (representative OA-EV sample). Red and blue histograms illustrate isotype controls and stained samples, respectively. (b) Transmission Electron Microscopy showing the cup-shape morphology of EVs (representative OA-EV sample, scale bar 200 nm). (c) Scatter plot showing size and number of particles/cell analysis of OA and control H-EVs, assessed by nanoparticle tracking analysis.
(a)
(b)
(c)