Strategies to Improve the Quality and Freshness of Human Bone Marrow-Derived Mesenchymal Stem Cells for Neurological Diseases

Table 1

Genes related to the transcriptomic network of the quality and freshness of starved human bone marrow-derived mesenchymal stem cells (hBM-MSCs).

Entrez gene name	Symbol	Affymetrix ID	Location	Signal (fold change)^a
				6 h	12 h
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma	PIK3CG	206370_at	Cytoplasm	-11.70	-22.42
erbb2 interacting protein	ERBIN	232896_at	Cytoplasm	-1.10	-19.71
Solute carrier family 25 member 27	SLC25A27	230624_at	Cytoplasm	-9.20	-12.39
BCL2 apoptosis regulator	BCL2	207005_s_at	Cytoplasm	-7.73	-9.99
Peroxiredoxin 3	PRDX3	209766_at	Cytoplasm	1.85	-9.27
NADPH oxidase 5	NOX5	1553023_a_at	Cytoplasm	1.70	11.82
Neutrophil cytosolic factor 4	NCF4	205147_x_at	Cytoplasm	-1.19	12.5
Protein kinase AMP-activated catalytic subunit alpha 2	PRKAA2	238441_at	Cytoplasm	12.61	22.26
Phosphatase and tensin homolog	PTEN	242622_x_at	Cytoplasm	3.62	54.26
Angiotensinogen	AGT	202834_at	Extracellular Space	1.04	-27.13
TNF superfamily member 14	TNFSF14	233935_at	Extracellular Space	-1.19	-23.12
Albumin	ALB	211298_s_at	Extracellular Space	8.07	-20.19
Alpha-microglobulin/bikunin precursor	AMBP	214425_at	Extracellular Space	-4.55	-10.51
Adiponectin, C1Q, and collagen domain containing	ADIPOQ	207175_at	Extracellular Space	-3.15	-10.1
Serpin family B member 5	SERPINB5	1555551_at	Extracellular Space	6.58	10.19
Insulin-like growth factor 1	IGF1	209542_x_at	Extracellular Space	8.20	17.32
von Hippel-Lindau tumor suppressor	VHL	203844_at	Nucleus	-1.33	-37.9
MacroH2A.1 histone	MACROH2A1	1558779_at	Nucleus	1.76	12.75
Integrin subunit beta 1	ITGB1	215878_at	Plasma Membrane	12.40	-36.23
Fibroblast growth factor receptor 2	FGFR2	211400_at	Plasma Membrane	4.66	-15.37
Low-density lipoprotein receptor	LDLR	217103_at	Plasma Membrane	-12.50	-11.9
Glutamate metabotropic receptor 5	GRM5	207235_s_at	Plasma Membrane	-10.02	-10.17
CD36 molecule	CD36	242197_x_at	Plasma Membrane	3.27	-9.46
Presenilin 1	PSEN1	1559206_at	Plasma Membrane	-2.64	9.57
Fc fragment of IgG receptor IIa	FCGR2A	203561_at	Plasma Membrane	13.11	13.69
Toll-like receptor 7	TLR7	220146_at	Plasma Membrane	2.10	24.72
Prostaglandin E receptor 3	PTGER3	210375_at	Plasma Membrane	-17.22	27.73

^aNormalized ratio of fold change of the signal at 6 and 12 h of storage, relative to the corresponding signal of the control group.