Chaetocin Promotes Osteogenic Differentiation via Modulating Wnt/Beta-Catenin Signaling in Mesenchymal Stem Cells
Effect of Chaetocin on MSC osteogenic differentiation. (a, b) Real-time RT-PCR analysis shows that expression of both early and later osteogenic markers (Runx2, OPN) was significantly enhanced by treatment with Chaetocin. (c, d) ALP staining showed a significant increase of ALP activity in MSCs treated with Chaetocin. (e, f) ARS staining showed a significant increase of calcium deposition in MSCs treated with Chaetocin. PCR and quantification data are expressed as of three independent experiments (). Scale bar: 100 μm.
Article of the Year Award: Outstanding research contributions of 2020, as selected by our Chief Editors. Read the winning articles.