Review Article

Clinical Efficacy and Safety of Human Mesenchymal Stem Cell Therapy for Degenerative Disc Disease: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Table 2

Subgroup analysis.

Responder analyses6 months12 months24 months36 monthsOverall effect

Pain responder
MIC in VAS [1.10, 5.84], [1.22, 6.36], [0.93, 4.48], [0.67, 3.34], [1.43, 3.25],
CSC in VAS [1.14, 5.90], [1.31, 7.12], [0.76, 4.16], [0.71, 3.71], [1.44, 3.31],
ODI responder
MIC in ODI [0.95, 4.92], [0.84, 4.15], [0.93, 4.84], [0.93, 4.84], [1.37, 3.10],
CSC in ODI [0.71, 3.58], [0.82, 4.23], [0.88, 4.47], [1.17, 6.74], [1.33, 3.05],