SOX12 Promotes Stem Cell-Like Phenotypes and Osteosarcoma Tumor Growth by Upregulating JAGGED1

Figure 5

SOX12 overexpression promotes the stem cell-like properties of osteosarcoma cells. (a) Transfection of SOX12 plasmid increased SOX12 mRNA in 143B cells. (b) Overexpression of SOX12 enhances the spheroidizing ability of 143B cells. (c) Overexpression of SOX12 enhances the spheroidizing ability of U2OS cells. (d) Overexpression of SOX12 upregulated the stemness markers of 143B cells.

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