Research Article
METTL3-Mediated m6A Methylation Regulates Muscle Stem Cells and Muscle Regeneration by Notch Signaling Pathway
Figure 4
METTL3 regulates m6A modification of Notch signaling pathway components. (a) Schematic representation of m6A MeRIP-Seq. (b) m6A motif identified in the MeRIP-Seq. (c) Enriched KEGG molecular function pathways identified from differentially m6A-enriched genes in METTL3 cKO vs. CTL D2 samples. (d) Notch signaling pathway identified in the MeRIP-Seq. (e, f) qRT-PCR and Western blot analyzed of Notch signaling pathway. CTL: control; cKO: METTL3 conditional knockout.
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