MSC-Derived Extracellular Vesicle-Delivered L-PGDS Inhibit Gastric Cancer Progression by Suppressing Cancer Cell Stemness and STAT3 Phosphorylation

<div>Ad-L-PGDS-modified huc-MSCs packaged L-PGDS into secreted EVs. (a) Representative fluorescence images of GFP in huc-MSCs after treatment with adenovirus for 24 h (×100). (b) Western blot for the expression of L-PGDS in adenovirus-transfected huc-MSCs after 24 h. (c) Western blot for the expression of EV markers CD9, CD63, and CD81 and the expression of L-PGDS in EVs. (d) TEM for the morphology of EVs. (e) NanoSight for the size of EVs. Abbreviations: TEM: transmission electron microscope.</div>

Stem Cells International

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Figure 2: MSC-Derived Extracellular Vesicle-Delivered L-PGDS Inhibit Gastric Cancer Progression by Suppressing Cancer Cell Stemness and STAT3 Phosphorylation 

Figure 2 | MSC-Derived Extracellular Vesicle-Delivered L-PGDS Inhibit Gastric Cancer Progression by Suppressing Cancer Cell Stemness and STAT3 Phosphorylation 