Platelet-Derived Mitochondria Attenuate 5-FU-Induced Injury to Bone-Associated Mesenchymal Stem Cells

Figure 7

Analysis of mRNA expression of hematopoietic regulatory factor genes and mitochondrial fusion/fission genes in BA-MSCs after mitochondrial treatment of BA-MSCs damaged by 5-FU. (a) Gene expressions of Opa1, Mfn1, Mfn2, Drp1, Mff, Fis1, and Mid51 in DMSO-treated BA-MSCs, 5-FU-treated BA-MSCs, and mitochondria-treated 5-FU-damaged BA-MSCs were detected by qRT-PCR (). (b) Gene expressions of Scf, Cxcl12, Thpo, Csfg, Csfm, Csfgm, and Il6 in DMSO-treated BA-MSCs, 5-FU-treated BA-MSCs, and mitochondria-treated 5-FU-damaged BA-MSCs were detected by qRT-PCR (). All data are presented as . Statistics: one-way ANOVA (ns: not significant; , , , and ).

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