Regenerative Potential of Granulation Tissue in Periodontitis: A Systematic Review and Meta-analysis
Table 1
Summary of demographics and study design from studies included in quantitative analysis.
Author, year of publication, and country
Study design
Definition of periodontitis
Ages (: periodontitis, : controls)
, periodontitis/controls
Sample collection site
Biomarkers measured
Pall et al., 2015, Romania
Case-control
Not mentioned
1/1
Granulation tissue: removed from the deepest part of surgical area (pocket reduction surgical approach, modified flap operation); healthy control: palatal tissue sample (premolar site), collected during mucogingival surgery (connective tissue graft plus coronally advanced flap)
Granulation tissue: removed from the deepest part of surgical area (pocket reduction surgical approach, modified flap operation); healthy control: connective tissue collected during a reentry surgery from the palatal premolar region that was already used as a donor site 6 months before