Stem Cells International

Molecular Imaging of Stems Cells: In Vivo Tracking and Clinical Translation


Status
Published

Lead Editor

1European Institute of Oncology, Milan, Italy

2University of Massachusetts, Boston, USA

3Harvard University, Boston, USA


Molecular Imaging of Stems Cells: In Vivo Tracking and Clinical Translation

Description

Molecular imaging is a rapidly emerging biomedical research discipline, providing integrated information on specific molecules within the cells, and holds great promise as a way to track certain cellular and subcellular events of transplanted cells.

The use of noninvasive, longitudinal, and quantitative imaging of stem cells, and their tracking after administration, might facilitate preclinical experimental studies in animal models, and stem cell therapy in human trials as well.

Molecular imaging modalities, as optical bioluminescence, optical fluorescence, targeted ultrasound, molecular magnetic resonance imaging (MRI), magnetic resonance spectroscopy (MRS), single-photon-emission computed tomography (SPECT), and positron emission tomography (PET), might help to investigate stem cells behaviors and feasibility of administration and therapy.

As experimental techniques progress, the potential benefits of regenerative medicine will be a strong motivation to improve imaging technology that will enable stem-cell-driven therapies to be more understood.

We invite investigators to contribute original research articles as well as review articles that will stimulate the continuing efforts to focus on advances in molecular imaging technologies and to provide insights into cell imaging and tracking following administration, in order to promote the clinical translation of stem-cell based therapies.

Potential topics include but are not limited to the following:

  • Advanced research in molecular imaging and biomarkers of stem cells
  • Development of novel labeling agents and theranostic imaging probes to image and track stem cells
  • Multimodality and novel imaging approaches for in vivo tracing stem cell: optogenetics imaging and stimulation, Raman imaging, Cerenkov imaging, magnetic particle imaging (MPI), MRI/PET, and others
  • Preclinical and clinical studies of in vivo imaging for stem cells transplantation

Articles

  • Special Issue
  • - Volume 2017
  • - Article ID 1783841
  • - Editorial

Molecular Imaging of Stems Cells: In Vivo Tracking and Clinical Translation

Stefania Rizzo | Francesco Petrella | ... | Ping Wang
  • Special Issue
  • - Volume 2016
  • - Article ID 4058656
  • - Review Article

Molecular Imaging of Stem Cell Transplantation for Liver Diseases: Monitoring, Clinical Translation, and Theranostics

Ping Wang | Francesco Petrella | ... | Stefania Rizzo
  • Special Issue
  • - Volume 2016
  • - Article ID 5029619
  • - Review Article

Towards Therapeutic Delivery of Extracellular Vesicles: Strategies for In Vivo Tracking and Biodistribution Analysis

Giuliana Di Rocco | Silvia Baldari | Gabriele Toietta
  • Special Issue
  • - Volume 2016
  • - Article ID 8610964
  • - Research Article

MRI-Based Assessment of Intralesional Delivery of Bone Marrow-Derived Mesenchymal Stem Cells in a Model of Equine Tendonitis

Alexandra Scharf | Shannon P. Holmes | ... | John Peroni
  • Special Issue
  • - Volume 2016
  • - Article ID 5457132
  • - Research Article

Label-Free Imaging of Umbilical Cord Tissue Morphology and Explant-Derived Cells

Raf Donders | Kathleen Sanen | ... | Niels Hellings
  • Special Issue
  • - Volume 2016
  • - Article ID 1691856
  • - Research Article

Dynamic Tracking Human Mesenchymal Stem Cells Tropism following Smoke Inhalation Injury in NOD/SCID Mice

MeiJuan Song | Qi Lv | ... | HaoJun Fan
  • Special Issue
  • - Volume 2016
  • - Article ID 4656539
  • - Research Article

Dynamic Tracking of Injected Mesenchymal Stem Cells after Myocardial Infarction in Rats: A Serial 7T MRI Study

Xiuyu Chen | Minjie Lu | ... | Shihua Zhao
  • Special Issue
  • - Volume 2016
  • - Article ID 3641401
  • - Research Article

Transplanted Endothelial Progenitor Cells Improve Ischemia Muscle Regeneration in Mice by Diffusion Tensor MR Imaging

Xin-Gui Peng | Yingying Bai | ... | Shenghong Ju
  • Special Issue
  • - Volume 2016
  • - Article ID 3970942
  • - Research Article

In Vivo Tracking of Systemically Administered Allogeneic Bone Marrow Mesenchymal Stem Cells in Normal Rats through Bioluminescence Imaging

Juan Cao | Shike Hou | ... | Haojun Fan
Stem Cells International
 Journal metrics
Acceptance rate44%
Submission to final decision76 days
Acceptance to publication35 days
CiteScore7.200
Impact Factor3.869
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