Stem Cells International

Skin Stem/Progenitor Cells in Skin Health, Diseases, and Treatment


Publishing date
01 Feb 2019
Status
Closed
Submission deadline
28 Sep 2018

Lead Editor

1University of Leipzig, Leipzig, Germany

2Technical University of Munich, Munich, Germany

This issue is now closed for submissions.
More articles will be published in the near future.

Skin Stem/Progenitor Cells in Skin Health, Diseases, and Treatment

This issue is now closed for submissions.
More articles will be published in the near future.

Description

Skin stem/progenitor cells hold great promise for regenerative medicine and cosmetic skin care. The success of stem cell-based approaches lies in the ability to understand and regulate skin stem cell populations in skin anatomy and physiology for skin repair and regeneration. Skin regeneration, either after injury or usually replacing dead skin in the ageing process, is critically regulated by cellular and molecular factors in the microenvironment of skin tissue during the lifespan of an organism. Cellular and molecular factors play an important role in activating stem cells to divide and transform into skin tissue-making cells. Under injury conditions or ageing process of skin, endogenous stem cell populations govern skin regeneration. Furthermore, skin stem cells approaches are routinely practiced for antiageing skincare. Skin stem cells are multipotent endogenous adult stem cells present in skin tissue, which have the capacity for self-renew and differentiate into different cell lineages of the skin under the influence of microenvironmental niches. In general, skin stem cells are silent but active during skin renewal and in skin repair after injury or ageing process. Current research reports bring new details to the understanding of how skin stem cells maintain and lose their status as local stem cells for skin regeneration.

The phenotype of skin approaches depends on environment and lifestyle, which involve cellular and molecular changes for skin appearance. In this special issue, we focus on recent cellular and molecular factors for regulation of stem cells for skin regeneration and how this may contribute to ageing, especially for skin repair and its appearance. To highlight the tremendous accumulating preclinical and clinical evidence about the endogenous stem cell and exogenous stem cell approaches for skin regeneration as well as cosmetic skin care, this special issue aims to publish new and current evidence for skin ageing and skin regeneration especially focusing on skin stem cells based treatment for several skin diseases including diabetic wound, skin burn, and cosmetic skin care.

The goal of this special issue is to gather the innovative approaches to direct future scientific efforts toward the clinical application of stem/progenitor cells in the treatment of skin diseases. To highlight the tremendous advances taking place in the field, this special issue aims to discuss new strategies for circumventing the hurdles in skin regeneration by exploiting exogenous and endogenous stem cells. Herein, the special issue aims to make more comprehensive understanding and identification of the impact of stem/progenitor cells in the treatment of skin disorders as well as skin disease modelling. Therefore, we welcome original research articles as well as review articles.

Potential topics include but are not limited to the following:

  • Endogenous stem cells system in skin anatomy and physiology in healthy skin and diseases conditions
  • Identification and characterization of novel stem/progenitor cell populations in skin tissues
  • Skin stem cells and their microenvironmental niches for skin repair and regeneration
  • Molecular and epigenetic mechanisms governing skin stem cell self-renewal and differentiation towards repair and regeneration
  • Signaling and cellular factors for skin regeneration
  • Combining approaches for nanostructured materials and skin stem cells for skin repair and regeneration
  • Dynamic interactions between microRNAs and skin stem cells /progenitor cells for balance self-renewal and early lineage commitment for skin repair and regeneration
  • Recent stem cell-based regenerative approaches for diabetic wounds and other skin injuries
  • Skin regeneration scaffolds for skin tissue engineering
  • Transdermal and topical drug delivery using stem cells: from theory to clinical practice/ cosmetic practice
  • Efficient gene editing in skin stem cells for treatment of skin diseases
  • Impact of dietary and lifestyle factors on skin regeneration and its appearance
  • Translational research and protocols of stem cells therapies for skin regeneration
  • Induced pluripotent stem cells based micro-physiological skin models for skin diseases modelling and their high-throughput screening

Articles

  • Special Issue
  • - Volume 2019
  • - Article ID 9320701
  • - Research Article

Expression of Potential Dermal Progenitor Cell Markers in the Tumour and Stroma of Skin Adnexal Malignant and Benign Tumours

Sven R. Quist | Maximilian Eckardt | ... | Harald P. Gollnick
  • Special Issue
  • - Volume 2019
  • - Article ID 9640790
  • - Research Article

Comparative Analysis of Biological Properties of Large-Scale Expanded Adult Neural Crest-Derived Stem Cells Isolated from Human Hair Follicle and Skin Dermis

Roman G. Vasyliev | Olga S. Gubar | ... | Dmytro O. Zubov
  • Special Issue
  • - Volume 2018
  • - Article ID 1353085
  • - Research Article

Fibrin Glue Enhances Adipose-Derived Stromal Cell Cytokine Secretion and Survival Conferring Accelerated Diabetic Wound Healing

Ursula Hopfner | Matthias M. Aitzetmueller | ... | Dominik Duscher
  • Special Issue
  • - Volume 2018
  • - Article ID 2183736
  • - Research Article

Single-Cell Gene Expression Analysis and Evaluation of the Therapeutic Function of Murine Adipose-Derived Stromal Cells (ASCs) from the Subcutaneous and Visceral Compartment

Dominik Pförringer | Matthias M. Aitzetmüller | ... | Dominik Duscher
  • Special Issue
  • - Volume 2018
  • - Article ID 1049641
  • - Review Article

Therapeutic Potential of Stem Cells in Follicle Regeneration

Agnieszka Owczarczyk-Saczonek | Magdalena Krajewska-Włodarczyk | ... | Joanna Wojtkiewicz
  • Special Issue
  • - Volume 2018
  • - Article ID 8631432
  • - Research Article

Hair Follicle Dermal Cells Support Expansion of Murine and Human Embryonic and Induced Pluripotent Stem Cells and Promote Haematopoiesis in Mouse Cultures

Jun Liu | Claire A. Higgins | ... | Colin A. B. Jahoda
  • Special Issue
  • - Volume 2018
  • - Article ID 8637812
  • - Review Article

The Human Skin-Derived Precursors for Regenerative Medicine: Current State, Challenges, and Perspectives

Ru Dai | Wei Hua | ... | Li Li
Stem Cells International
 Journal metrics
Acceptance rate44%
Submission to final decision76 days
Acceptance to publication35 days
CiteScore7.200
Impact Factor3.869
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