Stem Cells International

Stem Cells and Cardiac Repair


Status
Published

Lead Editor

1Temple University, Philadelphia, USA

2IRCCS, Milan, Italy

3University of Illinois, Chicago, USA


Stem Cells and Cardiac Repair

Description

Heart disease is the number one cause of death globally and accounts for more deaths annually than from any other source. In general, heart disease refers to conditions such as coronary artery disease, cardiac arrest, and congenital heart diseases. Heart disease is a huge burden on health care system and colossal amount of money is being spent each year to treat heart failure patients.

Current medical interventions are designed to be ‘damage limiting’ without offering true regeneration of the injured cardiac tissue. Stem cell therapy for heart disease has demonstrated promising results but is surrounded by a number of issues that have hampered development towards a cure for heart disease. Poor survival, cardiac lineage commitment, and depleted repair potential with age and disease pose significant barriers for stem cell based therapies to repair injured heart. Furthermore, the best stem cell for cardiac repair still remains open to debate and a number of recent controversial reports regarding the identity of the true resident heart stem cell have fuelled speculation about the overall efficacy of cell therapeutic approaches.

We welcome original research articles as well as review articles that would elucidate new findings and describe exciting challenges being faced in the field with possible solutions to help in the progression of stem cell therapy.

Potential topics include, but are not limited to:

  • Different stem cell types for cardiac repair
  • Modification of stem cells to enhance cardiac regeneration
  • Effect of disease on stem cell function
  • Aging and stem cells
  • Metabolism and stem cells
  • Safety and efficacy of stem cell therapeutics
  • Stem cells and epigenetics

Articles

  • Special Issue
  • - Volume 2015
  • - Article ID 153627
  • - Editorial

Stem Cells and Cardiac Repair

Sadia Mohsin | Daniele Avitabile | Mohsin Khan
  • Special Issue
  • - Volume 2015
  • - Article ID 496512
  • - Research Article

Particle Radiation-Induced Nontargeted Effects in Bone-Marrow-Derived Endothelial Progenitor Cells

Sharath P. Sasi | Daniel Park | ... | David A. Goukassian
  • Special Issue
  • - Volume 2015
  • - Article ID 176409
  • - Research Article

Bcl-xL Genetic Modification Enhanced the Therapeutic Efficacy of Mesenchymal Stem Cell Transplantation in the Treatment of Heart Infarction

Xiaodong Xue | Yu Liu | ... | Huishan Wang
  • Special Issue
  • - Volume 2015
  • - Article ID 765846
  • - Review Article

A New Paradigm in Cardiac Regeneration: The Mesenchymal Stem Cell Secretome

Clara Gallina | Valentina Turinetto | Claudia Giachino
  • Special Issue
  • - Volume 2015
  • - Article ID 638153
  • - Research Article

Pretreatment of Adipose Derived Stem Cells with Curcumin Facilitates Myocardial Recovery via Antiapoptosis and Angiogenesis

Jianfeng Liu | Ping Zhu | ... | Haibin Wang
  • Special Issue
  • - Volume 2015
  • - Article ID 691310
  • - Research Article

Ultrasound-Targeted Microbubble Destruction Improves the Migration and Homing of Mesenchymal Stem Cells after Myocardial Infarction by Upregulating SDF-1/CXCR4: A Pilot Study

Lu Li | Shengzheng Wu | ... | Yali Xu
  • Special Issue
  • - Volume 2015
  • - Article ID 659890
  • - Research Article

Exosomes Secreted from CXCR4 Overexpressing Mesenchymal Stem Cells Promote Cardioprotection via Akt Signaling Pathway following Myocardial Infarction

Kai Kang | Ruilian Ma | ... | Yigang Wang
Stem Cells International
 Journal metrics
Acceptance rate44%
Submission to final decision76 days
Acceptance to publication35 days
CiteScore7.200
Impact Factor3.869
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