Stem Cells International

Amniotic Stem Cells: Potential in Regenerative Medicine


Publishing date
22 Jun 2012
Status
Published
Submission deadline
03 Feb 2012

Lead Editor

1Neurogenesis and Brain Repair, National Research Council Canada-Institute for Biological Sciences, 1200 Montreal Road, Building M-54, Ottawa, ON, Canada K1A 0R6

2Wake Forest Institute for Regenerative Medicine, Wake Forest Baptist Health, Medical Center Boulevard, Winston-Salem, NC 27157, USA

3Institute of Medical Genetics, Medical University of Vienna, Währinger Straße 10, 1090 Vienna, Austria

4Department of Regenerative Medicine, University of Toyama Graduate School of Medicine and Pharmaceutical Sciences, 2630 Sugitani, Toyama 930-0194, Japan

5Key Laboratory of Regenerative Biology, South China Institute for Stem Cell Biology and Regenerative Medicine, Chinese Academy of Sciences, Guangzhou 510530, China


Amniotic Stem Cells: Potential in Regenerative Medicine

Description

Human amniotic fluid and amniotic membranes have received a great deal of attention as sources for novel fetal stem and progenitor cells with potential for regenerative medicine. Reports from several laboratories have shown that human amniotic fluid and membranes contain subpopulations of cells that are highly proliferative and have the capacity to differentiate into a variety of cell types. Furthermore, these cells demonstrate tropic support and exhibit low immunogenicity, suggesting their suitability for a wide range of clinical applications. However, there is an outstanding need to better understand the origin, lineage, genetic, and epigenetic regulatory mechanisms that underlie the biology of amniotic cells.

The goal of this issue on amniotic stem cells is to provide an opportunity to discuss different view points and recent findings that enhance our knowledge and facilitate potential applications and patient safety. Potential topics include, but are not limited to:

  • Cells in amniotic fluid: where are they from and where are they going?
    • Amniotic membranes: similar or different source of cells in amniotic fluid?
    • Amniotic fluid cells: stem cells, progenitors, discards or in transition?
    • What is their connection to mesenchymal stem cells?
    • Developmental lineage of cells in amniotic fluid and membranes: what do we know?
  • Gene and protein expression
    • MicroRNA regulation of gene expression
    • Epigenetic modifications in fetal cells
    • Proteomics of amniotic fluid and membrane cells. Are there any useful biomarkers?
  • Unique facets of signaling
    • Operant cell signaling pathways
    • Impact of maternal signaling molecules on fetal cells
  • Applications
    • Applications in drug screening
    • Applications in regenerative medicine and tissue engineering
    • Safety: when one transplantation is not enough
    • Ethical issues associated with their applications in humans

Before submission authors should carefully read over the journal's Author Guidelines, which are located at http://www.hindawi.com/journals/sci/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/ according to the following timetable:


Articles

  • Special Issue
  • - Volume 2012
  • - Article ID 530674
  • - Editorial

Amniotic Stem Cells: Potential in Regenerative Medicine

Mahmud Bani-Yaghoub | Patricia Wilson | ... | Duanqing Pei
  • Special Issue
  • - Volume 2012
  • - Article ID 721538
  • - Review Article

Applications of Amniotic Membrane and Fluid in Stem Cell Biology and Regenerative Medicine

Kerry Rennie | Andrée Gruslin | ... | Mahmud Bani-Yaghoub
  • Special Issue
  • - Volume 2012
  • - Article ID 485950
  • - Research Article

Clonal Populations of Amniotic Cells by Dilution and Direct Plating: Evidence for Hidden Diversity

Patricia G. Wilson | Lorna Devkota | ... | Zhan Wang
  • Special Issue
  • - Volume 2012
  • - Article ID 987185
  • - Research Article

Periostin as a Biomarker of the Amniotic Membrane

Mariya P. Dobreva | Larissa Lhoest | ... | An Zwijsen
  • Special Issue
  • - Volume 2012
  • - Article ID 607161
  • - Research Article

Human Amniotic Fluid Cells Form Functional Gap Junctions with Cortical Cells

Anna Jezierski | Kerry Rennie | ... | Mahmud Bani-Yaghoub
  • Special Issue
  • - Volume 2012
  • - Article ID 741810
  • - Review Article

Amniotic Fluid Stem Cells: Future Perspectives

Margit Rosner | Katharina Schipany | ... | Markus Hengstschläger
  • Special Issue
  • - Volume 2012
  • - Article ID 658356
  • - Research Article

Comprehensive Characterization of Mesenchymal Stem Cells from Human Placenta and Fetal Membrane and Their Response to Osteoactivin Stimulation

C. M. Raynaud | M. Maleki | ... | A. Rafii
  • Special Issue
  • - Volume 2012
  • - Article ID 107836
  • - Review Article

Amniotic Fluid and Amniotic Membrane Stem Cells: Marker Discovery

Maria G. Roubelakis | Ourania Trohatou | Nicholas P. Anagnou
  • Special Issue
  • - Volume 2012
  • - Article ID 709763
  • - Review Article

Amnion Epithelial Cells as a Candidate Therapy for Acute and Chronic Lung Injury

Ryan J. Hodges | Rebecca Lim | ... | Euan M. Wallace
Stem Cells International
 Journal metrics
Acceptance rate44%
Submission to final decision76 days
Acceptance to publication35 days
CiteScore3.800
Impact Factor3.902
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