Stem Cells International

Stem Cells: Microenvironment, Micro/Nanotechnology, and Application


Status
Published

Lead Editor

1Zhejiang University, Hangzhou, China

2Shanghai Jiaotong University, Shanghai, China

3National University of Singapore, Singapore

4Nanyang Technological University, Singapore

5University of Pittsburgh, Pittsburgh, USA

6University of Minho, Braga, Portugal


Stem Cells: Microenvironment, Micro/Nanotechnology, and Application

Description

Over the last decade, stem cells represent an ideal cell source for applications in tissue engineering, regenerative medicine and treatment of degenerative disease, autoimmune diseases, and Graft-versus-Host diseases. Several advances have been made in constructing artificial three-dimensional (3D) microenvironments to decipher the components of the stem cell niche and to probe the complex molecular mechanisms that regulate stem cell fate and functions including self-renewal, proliferation, differentiation, migration, and immune functions. Emerging biomaterial- and micro/nanotechnology-based platforms have advanced our understanding of the underlying mechanistic principles that govern the microenvironmental regulation of stem cell fate and functions in health and disease. More recently, it has been shown that the stem cell microenvironment not only influences stem cell fate and function, but also exerts profound effects on the secretome and extracellular matrix production of stem cells and tissue-resident cells, as well as overall tissue regeneration.

In light of the growing importance and impact of mesenchymal stem cell-based therapies, we invite reviews and original research papers that will facilitate understanding of the mesenchymal stem cell microenvironment, and offer potential strategies for clinical applications.

Potential topics include, but are not limited to:

  • Stem cell-biomaterials interactions
  • Stem cell secretome and its modulation
  • Endogenous stem cells in tissue repair
  • Immunomodulatory properties of stem cells
  • 3D cultures for stem cell research
  • Micro/nanotechnology in stem cell research

Articles

  • Special Issue
  • - Volume 2015
  • - Article ID 398510
  • - Editorial

Stem Cells: Microenvironment, Micro/Nanotechnology, and Application

Hua Liu | Zhiyong Zhang | ... | António Salgado
  • Special Issue
  • - Volume 2015
  • - Article ID 549432
  • - Research Article

Human Umbilical Cord Mesenchymal Stem Cells: A New Therapeutic Option for Tooth Regeneration

Yuanwei Chen | Yongchun Yu | ... | Lei Liu
  • Special Issue
  • - Volume 2015
  • - Article ID 507154
  • - Research Article

Electrospun Gelatin/-TCP Composite Nanofibers Enhance Osteogenic Differentiation of BMSCs and In Vivo Bone Formation by Activating Ca2+-Sensing Receptor Signaling

Xuehui Zhang | Song Meng | ... | Xuliang Deng
  • Special Issue
  • - Volume 2015
  • - Article ID 948040
  • - Review Article

Hydrogels and Cell Based Therapies in Spinal Cord Injury Regeneration

Rita C. Assunção-Silva | Eduardo D. Gomes | ... | António J. Salgado
  • Special Issue
  • - Volume 2015
  • - Article ID 752424
  • - Research Article

Modulating Mesenchymal Stem Cell Behavior Using Human Hair Keratin-Coated Surfaces

Pietradewi Hartrianti | Ling Ling | ... | Kee Woei Ng
  • Special Issue
  • - Volume 2015
  • - Article ID 484528
  • - Research Article

All-Trans Retinoic Acid Improves the Effects of Bone Marrow-Derived Mesenchymal Stem Cells on the Treatment of Ankylosing Spondylitis: An In Vitro Study

Deng Li | Peng Wang | ... | Huiyong Shen
  • Special Issue
  • - Volume 2015
  • - Article ID 804213
  • - Review Article

Graphene: A Versatile Carbon-Based Material for Bone Tissue Engineering

Nileshkumar Dubey | Ricardo Bentini | ... | Vinicius Rosa
  • Special Issue
  • - Volume 2015
  • - Article ID 525367
  • - Research Article

Modulation of Dental Pulp Stem Cell Odontogenesis in a Tunable PEG-Fibrinogen Hydrogel System

Qiqi Lu | Mirali Pandya | ... | Wei Seong Toh
Stem Cells International
 Journal metrics
Acceptance rate44%
Submission to final decision76 days
Acceptance to publication35 days
CiteScore7.200
Impact Factor3.869
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