Table of Contents Author Guidelines Submit a Manuscript

Enhanced Effect of Stem/Progenitor Cells in Repair and Regeneration in Lung Injury

Call for Papers

During the occurrence and development of lung injury (trauma, hemorrhagic shock, ischemia, and hypoxia), the integrity of tissues and organs may be destructed. Then, stem and progenitor cells are actively involved in the endogenous repairing courses as well as exogenous engraftment mainly under the guidance of neuroendocrine and immune system. The insightful disclosure of neuroendocrine immune network has remarkably improved our understanding of how the stem and progenitor cell-mediated repair keep resonance in lung injury.

Promisingly, the repair of organs and tissues has stepped into a prospective era of regenerative medicine. However, basic research and clinical practice in the functional repair and ideal lung regeneration remains crawling. Many confusing problems concerning the plasticity, lifetime, and outcome of stem and progenitor cells remain to be investigated. Their efficient mitigation, homing, and genetic engineering are vital for the ideal functional repair. Also, new findings of repairing mechanisms (neuroendocrine immune mediators, endogenous electric fields, growth factors, chemokines, etc.) by stem / progenitor cells are key to repair and regeneration in lung injury. Their tightly regulated courses comprising endoplasmic reticulum stress, apoptosis, and autophagy, microenvironment regulation, posttranscriptional splicing, posttranslational modifications, and metabolic regulations under the neuroendocrine immune network are essential for the prevention of pulmonary dysfunction.

Therefore, we solicit papers to be submitted to this special issue, reporting original data as well as reviews, which focus on topics related to stem/progenitor cells in repair and regeneration in lung injury from basic research to clinical practice.

Potential topics include but are not limited to the following:

  • Inflammation and immunity of mesenchymal stem cells and its metabolites in lung injury
  • Endothelial progenitor cells in repair and regeneration of lungs
  • Epidermal stem cells in the repair and regeneration of lungs
  • Role of adipose-derived stem cells in repair and regeneration of lungs
  • Lung stem/progenitor cells in endogenous repair and regeneration
  • Genetically engineered stem cells in repair and regeneration of lungs
  • Role of hematopoietic stem/progenitor cells in repair and regeneration of lungs
  • Role of modulators (hormones, transmitters, peptides, cytokines, mediators, electric fields, etc.) in the stem/progenitor cell-mediated repair and regeneration of lungs
  • Embryo-derived stem/progenitor cells in repair and regeneration of lungs
  • Influencing factors of stem/progenitor cells in repair and regeneration of lungs
  • Individualized therapy via stem/progenitor cells in repair and regeneration of lungs
  • Role of biomarkers in guiding therapy of stem/progenitor cells in repair and regeneration of lungs

Authors can submit their manuscripts through the Manuscript Tracking System at https://mts.hindawi.com/submit/journals/sci/eesp/.

Submission DeadlineFriday, 3 August 2018
Publication DateDecember 2018

Papers are published upon acceptance, regardless of the Special Issue publication date.

Lead Guest Editor

  • Ce Yang, Third Military Medical University, Chongqing, China

Guest Editors

  • Yun Zhao, Massachusetts General Hospital, Boston, USA
  • Hong Yu, Zhejiang University College of Medicine, Zhejiang, China