Table of Contents Author Guidelines Submit a Manuscript

Biofabrication for Stem Cell Engineering

Call for Papers

Three-dimensional (3D) biofabrication technology shows great promise for creating complex tissue constructs by spatial patterning living cells and biomaterials based on computer-aided design and micro/nano scale fabrication. The biofabrication technology has been used to develop living tissue and organ analogs for tissue engineering, regenerative medicine, pharmaceutical screening, and other biological studies. Given its great benefit in spatially arranging cells to recapitulate complex biological environment, biofabrication is also receiving enormous attentions in stem cell fields for controlling and engineering stem cell fate, since stem cells are responsive to their microenvironments and develop into special niches for specific functions. The biomaterials for fabrication provide the spectrum of biochemical (material chemistry, growth factors, adhesion molecules, etc.) and physical cues (tissue structure, mechanical properties, flow conditions, etc.) to promote stem cell survival, motility, self-renewal, and lineage-specific differentiation. Combination of biofabrication technologies and stem cell biology provides an opportunity for 3D vascularized tissues and organs for potential transplantation purposes.

The purpose of this special issue is to publish high-quality research articles as well as comprehensive reviews that relate to biofabrication technologies for stem cell and tissue engineering. Moreover, manuscripts focusing on biomaterial synthesis and biofabrication technology development are also welcome for submission.

Potential topics include but are not limited to the following:

  • Fabrication of in vivo-like microenvironment of stem cell niche
  • Biofabrication for controlling mesenchymal stem cell fate
  • Fabricating of stem cell organoids
  • Fabricating scale-up vascularized tissues and organs
  • Biofabrication for human iPS disease 3D tissue models
  • Regulating stem cell spatial differentiation in fabricated tissue constructs
  • Stem cell-laden bioprinting
  • Controlling stem cell-based tissue morphogenesis

Authors can submit their manuscripts through the Manuscript Tracking System at

Submission DeadlineFriday, 22 June 2018
Publication DateNovember 2018

Papers are published upon acceptance, regardless of the Special Issue publication date.

Lead Guest Editor

  • Zhen Ma, Syracuse University, Syracuse, USA

Guest Editors