Scientifica / 2012 / Article / Tab 1

Review Article

B Cells in Autoimmune Diseases

Table 1

Examples for receptor autoantibodies.

Targeted receptorMechanismAssociated diseaseReferences

Endothelial receptor type A (ETAR)ActivationPulmonary arterial hypertension (PAH)[1]
Angiotensin II receptor (AT1R), ETARActivation Systemic sclerosis[2]
AT1RActivatingPreeclampsia[35]
-adrenergic receptors (α 1-ARs)ActivatingRefractory hypertension[3, 6, 7]
-adrenergic receptorActivation Dilated cardiomyopathy (DCM), Chagas’ disease[8, 9]
N-methyl-D-aspartate receptor (NMDAR)Activation SLE[10]
Glutamate receptorActivation SLE[11]
Insulin receptorInhibitionAutoimmune hypoglycemia[12]
Muscarinic type 3 receptorInternalizationSjögren's syndrome[13]
NMDARInternalizationAnti-NMDA receptor encephalitis[14]