In Search of an Accurate Evaluation of Intrahepatic Cholestasis of Pregnancy

Table 1

Clinical and biochemical characteristics of women with ICP and women with normal pregnancies.

	Groups studied
	Normal pregnancies	ICP (low pruritus score)	ICP (high pruritus score)
Number of subjects	38	9	23
Age in years (range)	27 (23–39)	31 (24–39)	27 (21–33)
Number of pregnancies (n)	1.8	1.9	2.3
History of ICP (n)	0	5	5
Familiar history of ICP (n)	0	5	5
Total bilirubin (mg/mL)	0.40±0.02	0.40±0.03	0.83±0.08^∗
AST (IU/L)	21.0±1.5	21.0±3.0	92.0±13.2^∗∗
ALT (IU/L)	14.4±0.8	17.0±2.7	128±25^∗∗
ALP (IU/L)	313±20	282±56	674±50^∗∗
γ-GT (IU/L)	38±9	36±11	33±3
5^NT (IU/L)	7.8±1.9	7.2±2.4	7.9±2.6

Results are expressed as means ± SEM. For total bilirubin, the normal range is up to 1.1 mg/dL. The normal ranges for AST, ALT, and ALP are 12–31, 12–40, and 90–240 IU/L, respectively. For γ-GT and 5^NT, the normal ranges are up to 40 and 9.7 IU/L, respectively.
^*𝑃<0.05 and ^**𝑃<0.01 compared with normal pregnancies.