A Comparison of Two Classes of Methods for Estimating False Discovery Rates in Microarray Studies

Figure 1

ROC curves for the t-statistic (black line), s30-statistic (red line), s50-statistic (blue line), s70-statistic (green line), and s90-statistic (purple line) in a type EV simulation. In each plot the horizontal axis is the false positive fraction and the vertical axis is the true positive fraction. The sample sizes in the two groups vary from 8 and 6 (left column) to 60 and 45 (right column). 𝜋₁ denotes the proportion of differentially expressed genes.