Clinical Pharmacology in Old Persons

Table 6

Common undertreated conditions and advised medication according to guidelines.

Disease or problem	Advised medicines
Angina pectoris	beta-receptor blocking drug
Atrial fibrillation	VKA, when contraindicated acetylsalicylic acid
Cardiovascular disease^1	in case of oversensitiveness: clopidogrel, prasugrel
Cardiovascular disease + LDL > 2.5	Statin
Cerebral infarction/TIA	Consider antihypertensive treatment, even with normal blood pressure
COPD	Inhalation ipratropium or tiotropium/β2-agonists
Corticosteroids used > 1 month	Medication to prevent osteoporosis: bisphosphonates
Depression	Antidepressants: SSRI’s or nortriptyline
Diabetes Mellitus	Lipid lowering drugs
Diabetes with proteinuria	ACE-inhibitor
Heart failure	ACE-inhibitor, or AT II antagonist if necessary beta-receptor blocking drug
Hypertension	Anti-hypertensive treatment
Insufficient daylight	Vitamin D3
Myocardial Infarction	Acetylsalicylic acid, ACE-inhibitor, beta-receptor blocking drug
NSAID	Gastric protection with Proton Pump Inhibitors
Opioids	Laxatives
Osteoporosis	Antiosteoporosis drugs
Pain	Analgesics

1Cardiovascular disease: by atherothrombotic processes caused clinical manifestations, like myocardial infarction, angina pectoris, cerebral infarction, transient ischaemic attack (TIA), aortic aneurysm, and peripheral arterial vessel disease.