Scientifica / 2012 / Article / Tab 4

Review Article

The Insulin-Like Growth Factor System and Nutritional Assessment

Table 4

Possible clinical utility for measurement of serum IGF axis proteins.

Reference

IGF-I
Prediction of ITx patients requiring intensive nutritional intervention following transplant[76]
Index of IF in children with SBS[75]
Monitoring of recombinant GH treatment[77]
Monitoring of PN and nitrogen balance[74]
Indicator of short-term change in nutritional status[36]
Prediction of refeeding risk and mortality[98]
Diagnosis of acromegaly[99]
Diagnosis of growth hormone deficiency[99]

IGF-II
Diagnosis of NICTH[13]
Monitoring of refeeding[34]

IGFBP-1
Assessment of insulin resistance and cardiovascular risk[96]
Marker for metabolic syndrome[53]
Prediction of growth failure in chronic renal disease[97]
Prediction of development of insulin resistance in children[54]
Monitoring of life-style interventions[95]

IGFBP-2
Marker for metabolic syndrome[55]
Diagnosis of NICTH[100]

IGFBP-3
Monitoring of nutritional status[58]
Assessment of GH status[101]
Monitoring of GH treatment[101]

Key: ITx: intestinal transplant; IF: intestinal failure; SBS: short bowel syndrome; NICTH: non-islet cell tumour hypoglycaemia.

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