The Role of the Dysfunctional Akt-Related Pathway in Cancer: Establishment and Maintenance of a Malignant Cell Phenotype, Resistance to Therapy, and Future Strategies for Drug Development

Table 1

Coordinates of the Akt activating threonine (Thr) and serine (Ser) residues among the three Akt isoforms.

Akt isoform	Position of Akt activating Thr residue	Position of Akt activating Ser residue
Akt1	308	473
Akt2	309	474
Akt3	305	472