Scientifica / 2013 / Article / Tab 1 / Review Article
Hox Targets and Cellular Functions Table 1 Microarray expression profile and ChIP methods used to identify Hox targets. The Hox genes are studied in the wildtype, in Hox mutants, or after Hox ectopic expression. Modified from [
47 ].
Organism Hox gene Tissue Method Reference Drosophila lab Whole embryo Microarrays [53 ] Drosophila Antp, Scr, and Ubx Imaginal discs Microarrays [54 ] Drosophila Scr Leg imaginal discs Microarrays [61 ] Drosophila Ubx Haltere and wing imaginal discs Microarrays [64 ] Drosophila Ubx Haltere and wing imaginal discs Microarrays [66 ] Drosophila Dfd, Antp, Scr, Ubx, abd-A, and Abd-B Whole embryo Microarrays [67 ] Drosophila Ubx Haltere and wing imaginal discs Microarrays [73 ] Drosophila Ubx Haltere imaginal disc ChIP [76 ] Drosophila Ubx Haltere and third leg imaginal discs ChIP [77 ] Drosophila Ubx Haltere imaginal disc ChIP [78 ] Drosophila Dfd Whole embryo ChIP [79 ] Mouse Hoxa13 Uterus and cervix Microarrays [52 ] Mouse Hoxa11 Kidney cell lines Microarrays [55 ] Mouse Hoxd10 Spinal cord Microarrays [56 ] Mouse Hoxc8 Embryonic fibroblasts Microarrays [57 ] Mouse Hoxa13 Embryonic fibroblasts Microarrays [58 ] Mouse Hoxd cluster genes Limb and genital tissue Microarrays [59 ] Mouse Hoxa1 Embryonic stem cells from blastocysts Microarrays [60 ] Human Hoxa9, Hoxa10 Umbilical cord cells Microarrays [62 ] Mouse Hoxa11, Hoxd11 Kidney Microarrays [63 ] Mouse Hoxa1, Hoxb1 Whole embryos Microarrays [65 ] Mouse Hoxa2, Hoxb1, Hoxb2 Hoxb3, and Hoxd3 Rhombomeres 2–5 Microarrays [69 ] Mouse Hoxc13 Skin Microarrays [71 ] Mouse Hoxa1 Rhombomeres 3–5 Microarrays [72 ] Mouse Hoxa13 NIH 3T3-derived embryonic fibroblasts ChIP [74 ] Human Hoxd13 Humeral bone ChIP [75 ] Mouse Hoxa2 Second branchial arch ChIP [80 ] Zebrafish Hoxb1a Whole embryo Microarrays [68 ] Zebrafish Hoxb1b Whole embryo Microarrays [70 ]
