Figure 1: Biotin network in plants. Schematic map of the metabolism associated with biotin. Metabolites’ names are in black text. Red arrows represent the biotinylating actions of HCS on biotin-dependent proteins. Black arrows represent other metabolic reactions characterized in plants. Enzymes identified by direct biochemical evidences are shaded in green boxes. Grey-dotted arrows represent the reactions characterized in humans or E. coli but not in plants so far. Enzymes not identified in plants but characterized in humans or E. coli are shaded in grey boxes.