Ionotropic GABA Receptors and Distal Retinal ON and OFF Responses

Table 2

Effects of GABA and GABA antagonists on the light responses and centre-surround organization of the receptive fields of the ON and OFF bipolar cells.

BCs type	Effects on light responses			Effects on centre-surround organization	Species	References
	GABA	GABAAR antagonists	GABACR antagonists
ON BCs	Decreased	Increased	Increased	Preserved	Mudpuppy	[177]
		Decreased		Eliminated	Mudpuppy	[178]
	Slight reduction			Eliminated	Xenopus	[179]
	No effect				Carp	[180]
		Increased*			Rat	[181]
OFF BCs	Decreased	No effect	No effect	Preserved	Mudpuppy	[177]
		No effect			Mudpuppy	[178]
	Decreased			Preserved	Xenopus	[179]
	Decreased				Carp	[180]
	Decreased	Decreased	Decreased	Preserved	Tiger salamander	[182]
	Decreased			Eliminated	Tiger salamander	[183]

∗Combined application of GABA_A + GABA_C antagonists.