Review Article

Volatile Anaesthetic Depression of the Carotid Body Chemoreflex-Mediated Ventilatory Response to Hypoxia: Directions for Future Research

Figure 2

(a) Standardised anaesthetic effect on hypoxic response for each of the studies in Table 1. The horizontal dashed line indicates that at a value of <1.0 for standardised anaesthetic effect implies depression of hypoxic response by agent; a value of 1.0 indicates no effect and a value >1.0 suggests stimulation by agent. Each study is plotted by size (diameter) of the symbol (smallest ; largest ). The dark symbol represents the weighted mean value and error bars ±95% confidence intervals. (b) Standardised anaesthetic effect on hypercapnic response for each of the studies in Table 1. Within each panel the solid line indicates the best fit line (linear weighted least squares regression). The best fit equation for hypoxia is ; that for hypercapnia is .
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(a)
394270.fig.002b
(b)