Walking along the Fibroblast Growth Factor 10 Route: A Key Pathway to Understand the Control and Regulation of Epithelial and Mesenchymal Cell-Lineage Formation during Lung Development and Repair after Injury

<table><i>Epithelial progenitor cells in the adult lung after injury</i>. (a) AECII serve as progenitors for AECI and they self-renew after hyperoxic injury. (b) In case of more pronounced injury, variant Clara cells serve as progenitors for the secretory and ciliated lineages as well as AECII. More recently, other progenitors have emerged such as (c) the α6<i>β</i>4-double positive cells that can give rise to both alveolar and bronchiolar progenitors, (d) the basal-cell-“like” pods giving rise to variant Clara cells and AECII, and (e) the BASC also giving rise to variant Clara cells and AECII.</table>

Scientifica

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Figure 9

Figure 9: Walking along the Fibroblast Growth Factor 10 Route: A Key Pathway to Understand the Control and Regulation of Epithelial and Mesenchymal Cell-Lineage Formation during Lung Development and Repair after Injury 

Figure 9 | Walking along the Fibroblast Growth Factor 10 Route: A Key Pathway to Understand the Control and Regulation of Epithelial and Mesenchymal Cell-Lineage Formation during Lung Development and Repair after Injury 