Efficacy of 1.5% Dish Washing Solution and 95% Lemon Water in Substituting Perilous Xylene as a Deparaffinizing Agent for Routine H and E Staining Procedure: A Short Study

Table 1

Health hazards of xylene (Kandyala et al. [1]).

SNO	System	Effect
1	Nervous system	100–200 ppm → nausea and headache.
		200–500 ppm → dizziness, weakness, and vomiting.
		800–10,000 ppm → giddiness, confusion, slurred speech, loss of balance, and ringing sound.
		>10,000 ppm → sleepiness, loss of consciousness, and death.
2	GIT	Nausea, vomiting, and gastric discomfort.
3	ENT	Irritation and damage to eye (accidental splash).
4	Muscle	Reduced grasping power and reduced muscle power in extremities.
5	Skin	Irritation, dermatitis, dryness, and flaking and cracking of skin.
6	Cancer	Carcinogenic in animals.
7	Reproductive	Delayed ossification and contaminates breast milk.
8	Lungs	Irritation, chest pain, and shortness of breath (200 ppm).
		Pulmonary edema (extreme conditions).
9	Liver and kidney	Injury.