Influenza Viral Manipulation of Sphingolipid Metabolism and Signaling to Modulate Host Defense System
Modulation of influenza virus amplification by sphingosine kinase 1 and S1P lyase. SK1 increases influenza virus replication, whereas S1P lyase inhibits virus propagation. Manipulation of SK1 such as SK1 inhibition suppresses production of infectious influenza viruses.
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