Review Article

Detection of Circulating Tumor Cells

Table 1

Summary of CTC counts in 7.5 mL of blood from patients ( ) with various types of metastatic carcinomas. It represents the percentage of patients (%) from the total group of patients ( ) above a certain CTC cut-off, detected with the CellSearch System.

% ( ) ≥ 1% ( ) ≥ 2% ( ) ≥ 3% ( ) ≥ 5% ( ) ≥ 10% ( ) ≥ 50% ( ) ≥ 100References

Subject
 Healthy2(330)0.3(330)0(185)0(330)0(330)0(330)0(330)[4, 13, 4749]
 Nonmalignant5(398)1(398)0(101)0(101)0(101)0(101)0(101)[4, 47]

Metastatic cancer type
 Bladder 47(53)35(20)25(53)5(20)0(20)0(53)[50, 51]
 Breast 55(200)53(562)33(91)38(671)32(562)18(268)12(562)[4, 47, 5255]
 Colorectal 48(545)34(455)32(676)18(455)12(455)0(42)0(455)[8, 5659]
 Gastric 67(27)56(27)41(27)26(27)19(27)4(27)4(27)[13]
 Lung, non-small cell46(57)28(117)20(20)11(57)10(20)5(20)5(20)[53, 60, 61]
 Lung, small cell95(38)89(62)79(38)79(38)74(38)53(38)47(38)[12, 62]
 Ovarian 14(216)[15]
 Pancreatic 35(72)19(72)15(72)8(72)7(72)3(72)3(72)[63, 64]
 Prostate 60(149)80(40)66(95)59(314)53(40)33(40)18(40)[10, 48, 49, 53, 65, 66]