TY - JOUR
A2 - Ward, Diane
AU - Zhao, Bing
AU - Chen, Ye-Guang
PY - 2014
DA - 2014/09/23
TI - Regulation of TGF-β Signal Transduction
SP - 874065
VL - 2014
AB - Transforming growth factor-β (TGF-β) signaling regulates diverse cellular processes, including cell proliferation, differentiation, apoptosis, cell plasticity, and migration. TGF-β signaling can be mediated by Smad proteins or other signaling proteins such as MAP kinases and Akt. TGF-β signaling is tightly regulated at different levels along the pathways to ensure its proper physiological functions in different cells and tissues. Deregulation of TGF-β signaling has been associated with various kinds of diseases, such as cancer and tissue fibrosis. This paper focuses on our recent work on regulation of TGF-β signaling.
SN - null
UR - https://doi.org/10.1155/2014/874065
DO - 10.1155/2014/874065
JF - Scientifica
PB - Hindawi Publishing Corporation
KW -
ER -