Macrophage Heterogeneity and Plasticity: Impact of Macrophage Biomarkers on Atherosclerosis

Figure 2

Monocyte heterogeneity. According to differential expression of specific cell surface markers and receptors, monocytes may be classified into three distinct subpopulations: “classic” monocytes [CD14⁺⁺CD16⁻], “intermediate” monocytes [CD14⁺⁺CD16⁺], and “nonclassic” monocytes [CD14⁺CD16⁺⁺].