Research Article

Biological Evaluation of Pupalia lappacea for Antidiabetic, Antiadipogenic, and Hypolipidemic Activity Both In Vitro and In Vivo

Table 2

Effect of Pupalia lappacea in blood glucose primed rats.

S. numberTreatment groupDose (mg/kg)Blood glucose level (mg/dL)
0 h30 min90 min

1NCUntreated78 ± 3.776 ± 2.974 ± 1.9
2GPVehicle87 ± 3.3184 ± 6.3152 ± 4.3
3RF5.090 ± 3.9152 ± 3.296 ± 3.8
4AS00125086 ± 2.9153 ± 6.2119 ± 2.6
5AS00250088 ± 2.8151 ± 3.2110 ± 1.3

NC = normoglycemic control, GP = glucose primed, and RF = reference group (glibenclamide, 5.0 mg/kg). Values are expressed as mean ± SEM (number of animals, ), significantly different at , when compared with diabetic control group, # refers to “Time post glucose administration”.