Biological Evaluation of Pupalia lappacea for Antidiabetic, Antiadipogenic, and Hypolipidemic Activity Both In Vitro and In Vivo

Table 3

Effect of Pupalia lappacea in blood glucose level of STZ induced diabetes in rats.

S. number	Treatment group	Dose (mg/kg)	Blood glucose level (mg/dL)
			Day 0	Day 7	Day 14	Day 21	Day 28
1	NC	Untreated	78.67 ± 2.51	92.61 ± 5.01	90.78 ± 12.49	88.46 ± 4.38	84.26 ± 5.48
2	DC	Vehicle	80.03 ± 3.60	364.27 ± 16.17	351.62 ± 21.92	338.12 ± 17.24	340.68 ± 11.24
4	RF	5.0	76.83 ± 8.52	344.21 ± 9.58	340.01 ± 14.65	261.36 ± 3.11	119.59 ± 9.75
5	AS001	250	84.04 ± 3.14	361.83 ± 6.37	341.60 ± 18.86	303.21 ± 6.58	234.68 ± 5.74
6	AS002	500	78.78 ± 3.88	346.53 ± 2.30	333.11 ± 17.12	284.82 ± 6.05	211.61 ± 3.41

NC = normoglycemic control, DC = diabetic control, and RF = reference group (glibenclamide, 5.0 mg/kg). Values are expressed as mean ± SEM (number of animals, ), significantly different at , when compared with diabetic control group.