| | Class | Drugs/hormones | Reported amounts (μg/L)/country | References |
| | Antipyretics for reducing fever | Aspirin | 0.22 (Germany), 13 (Greek, Spain) | [46] | | Naproxen | <0.1 (USA), 0.958 (EU), 0.108 (Spain), 0.7 (Poland) | [2, 45, 47] | |
Analgesics for pain relief | Paracetamol/acetaminophen | 0.211 (USA), 10 (USA), 10.19 (Spain) | [16, 18, 47] | | Ibuprofen | 516 (USA), 0.174 (China), 2.5 (Poland), 70.35 (USA), 6.0 (Spain) | [2, 30, 39, 47, 48] | | Antibiotic for treating bacterial infections | Metronidazole | 0.176 (Spain), 0.9 (Switzerland) | [20, 39] | | Tetracycline | 0.10 (USA), 0.4 (Serbia), 0.69 (Spain), 0.023 (Spain) | [16, 24, 33, 47] | | Amoxicillin | 0.12 (Spain), 2.69–31.71 (Tanzania) | [36, 47] | | Antimalaria | Artemether
Lumefantrine | No immediate report as this medication is mainly used in Tanzania | Not reported | | Hormone replacement | Estrone | 0.0004 (USA), 0.0001–0.00157 (France), 0–0.67 (Ecuador), 0.0001–0.017 (USA) | [3, 7, 18, 19] | | Progesterone | 1.0 (USA), 3.1 (USA), 0.005 (USA) | [1, 16, 19, 46] | | β-blocker for treating abnormal heart rhythms | Atenolol | 0.4 (Spain), 0.036 (USA), 0.86 (USA), 1.872 (Spain), 0.026 (USA) | [18, 39, 46, 47] | |
Estrogen, endocrine disrupting hormones | Estradiol | 0.017 (USA), 0.0014–0.002 (Netherlands), 0–0.670 (Ecuador), 0.0002 (USA) | [3, 19, 46, 49] | | Estriol | 0.0004 (USA), 0.0049–0.0121 (France), 0.005 (USA), 0.005 (USA) | [7, 16, 19, 34] |
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