Research Article

Development and Characterization of Novel Floating-Mucoadhesive Tablets Bearing Venlafaxine Hydrochloride

Table 5

Comparative study of various granules characteristics.

Formulation codeAngle of repose ()Flow rate (gm/second)Bulk density (gm/cm3)Tapped density Carr’s index

FC124.70 ± 1.821.18 ± 0.020.672 ± 1.260.826 ± 1.0618.64
FC225.98 ± 1.741.13 ± 0.170.651 ± 0.280.817 ± 1.0220.32
FC326.89 ± 1.020.98 ± 0.110.681 ± 0.400.887 ± 0.8023.22
FC428.12 ± 1.160.91 ± 0.130.648 ± 0.160.862 ± 0.5024.82
FC531.09 ± 0.821.10 ± 0.120.624 ± 1.080.801 ± 0.1822.10
FC631.47 ± 1.110.99 ± 0.090.667 ± 0.300.907 ± 1.2026.46
FC737.39 ± 1.730.95 ± 0.050.662 ± 0.240.901 ± 0.3026.53
FC832.15 ± 1.040.98 ± 0.030.652 ± 1.010.807 ± 1.0819.21
FC927.08 ± 1.321.07 ± 0.070.664 ± 0.360.823 ± 0.4519.32
FC1030.07 ± 1.511.05 ± 0.190.694 ± 0.500.852 ± 0.1618.54
FC1131.09 ± 0.861.21 ± 0.160.701 ± 0.300.905 ± 0.1022.54
FC1226.06 ± 0.871.22 ± 0.100.721 ± 0.180.910 ± 1.2320.77
FC1322.29 ± 0.851.20 ± 0.080.736 ± 0.100.899 ± 0.3518.13

Mean ± SD; ; FC: formulation code.