Ameliorative Effect of Chronic Supplementation of Protocatechuic Acid Alone and in Combination with Ascorbic Acid in Aniline Hydrochloride Induced Spleen Toxicity in Rats

Table 1

Effect of PCA alone and in combination with AA on body weight, spleen weight, water intake, and feed consumption.

Parameters	Control	AH	AH+PCA	AH+AA	AH+PCA+AA
Body weight (g)	262.5 ± 4.433	178.0 ± 2.129	194.7 ± 2.362^#	199.3 ± 2.305^##	228.7 ± 4.063
Spleen weight (g)	0.701 ± 0.027	1.331 ± 0.036	0.896 ± 0.030^##	0.924 ± 0.030^##	0.858 ± 0.032
Spleen hypertrophy	0.00267	0.00747	0.00460^##	0.00463^##	0.00375
Water intake (mL)	37 ± 0.966	18.33 ± 0.557	22 ± 0.730^##	28.77 ± 0.432^##	39.21 ± 0.747
Feed consumption (g)	18.31 ± 0.21	12.04 ± 0.220	13.49 ± 0.358^##	13.73 ± 0.338^##	17.97 ± 0.312

Values are expressed as mean ± SEM. Level of significance is considered as p < 0.05, , and compared to control group. , , and compared to AH-treated group. compared to AH+PCA and compared to AH+AA group.