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Volume 2016 (2016), Article ID 4381067, 8 pages
Research Article

Role of Wheat Based Diet on the Pathology of Necrotic Enteritis in Turkeys

1National Veterinary School of Toulouse, Toulouse, France
2Department of Pathobiology, Faculty of Veterinary Sciences, University of Arid Agriculture, Rawalpindi, Pakistan
3Department of Pathobiology, College of Veterinary & Animal Sciences, Jhang, Pakistan
4Department of Pathology, University of Veterinary & Animal Sciences, Lahore, Pakistan
5Veterinary Research Institute (VRI), Lahore, Pakistan
6Nantes Atlantic National College of Veterinary Medicine, Food Science and Engineering, Nantes 44300, France

Received 25 December 2015; Revised 26 March 2016; Accepted 7 April 2016

Academic Editor: Haiqi He

Copyright © 2016 Sajid Umar et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


The study was conducted to investigate the effects of wheat based diet on the pathology of necrotic enteritis in turkeys. Turkeys were divided into four groups. Groups A and B were kept as noninoculated and fed normal commercial diet while groups C and D were challenged orally with C. perfringens and fed wheat based diet to promote the development of experimental disease. Infected turkeys showed clinical signs of depression, ruffled feathers, and dark yellowish faeces showing the most prominent disease signs in turkeys of group D with 30% mortality. Similarly, turkeys of group D showed more striking gross and histopathologic lesions as compared to turkeys of group C. The most severe gross lesions comprised intestinal distension, small necrotic spots and haemorrhages on intestine, fragile intestinal wall, and gas bubble formation in the small intestine. Histologically, inoculated turkeys showed patchy necrosis, desquamation of intestinal epithelium, and intense leukocyte infiltration in the intestine. Microscopic examination showed significant decrease in the height of intestinal villi of inoculated birds. Haematological studies showed significant influence of necrotic enteritis on the blood profile of turkeys in group D. The findings revealed that simultaneous feeding of wheat enhanced the pathology of necrotic enteritis in turkeys.