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Volume 2016, Article ID 6303815, 4 pages
Research Article

Changes in Mitral Annular Ascent with Worsening Echocardiographic Parameters of Left Ventricular Diastolic Function

1University of Puerto Rico School of Medicine, P.O. Box 365067, San Juan, PR 00936-5067, USA
2Cardiovascular Medicine Division, University of Puerto Rico School of Medicine, Medical Sciences Campus, P.O. Box 365067, San Juan, PR 00936-5067, USA

Received 2 December 2015; Revised 4 February 2016; Accepted 8 February 2016

Academic Editor: Michael S. Firstenberg

Copyright © 2016 Paula M. Hernández Burgos and Angel López-Candales. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Background. While the mitral annular plane systolic excursion (MAPSE) has been suggested as a surrogate measurement of left ventricular ejection fraction, less is known about the relative value of mitral annular ascent (MAa). Methods. Our database was queried for complete transthoracic echocardiograms performed for any clinical indication. Baseline echocardiographic measurements were compared to determine any correlation between MAa and traditional Echo-Doppler echocardiographic measures to characterize left ventricular diastolic dysfunction (LVDD). Results. Patients with normal LV diastolic function were younger ( years) than patients with LVDD (stage 1: years; stage 2: years; and stage 3: years; ). LV ejection fraction decreased in patients with stage 2 LVDD (%) and was further reduced in patients with stage 3 LVDD (; ). Discussion. While a vigorous MAa excursion was seen in patients with stage 1 LVDD, MAa significantly decreased in stage 2 and stage 3 LVDD patients. Our results highlight the importance of atrioventricular coupling, as MAa motion seems to reflect changes in left atrial pressure. Additional studies are now required to better examine atrioventricular interactions and electromechanical coupling that might improve our assessment of LV diastolic function.