Research Article

In Vitro and In Vivo Evaluation of Niosomal Formulation for Controlled Delivery of Clarithromycin

Table 4

Effect of storage on particle size at refrigerated and room temperature.

Formulation codeDays intervalParticle size (m)
InitialRefrigerated temperatureRoom temperature

NC27th day4.674 ± 0.0284.681 ± 0.021 4.711 ± 0.037
14th day4.703 ± 0.0194.809 ± 0.062
21st day4.741 ± 0.0404.894 ± 0.044
28th day4.793 ± 0.0295.014 ± 0.057
30th day4.871 ± 0.0335.331 ± 0.041