Vasorelaxation Effect of Estrone Derivate EA204 in Rabbit Aorta
Inhibitory activities of EA204 (10 μM) and verapamil (0.1 μM) on the concentration-response curves of CaCl2 (10−6 to 10−2 M) on denuded aortic rings of rabbits. Endothelium was removed mechanically by rubbing with a steel wire. Responses are expressed as a percentage of the maximum contraction induced by CaCl2 (10−2 M). Values indicated the means ± SEM ().
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