Vasorelaxation Effect of Estrone Derivate EA204 in Rabbit Aorta
Cumulative concentration-response curves of EA204 in the absence or presence of glibenclamide (10−5 M) on denuded aortic rings of rabbits precontracted with BaCl2 (2 mg/mL). Endothelium was removed mechanically by rubbing with a steel wire. Responses are expressed as a percentage of the maximum possible relaxation, that is, relaxation back to the baseline tension. Values indicated the means ± SEM ().
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