Research Article
Oral Feeding of Probiotic Bifidobacterium infantis: Colonic Morphological Changes in Rat Model of TNBS-Induced Colitis
Table 1
Criteria for scoring macroscopic colonic damage.
| Score | Criteria |
| 0 | No damage | 1 | Hyperemia, no ulcers | 2 | Linear ulcer with no significant inflammation | 3 | Linear ulcer with inflammation at one site | 4 | Two or more sites of ulceration/inflammation | 5 | Two or more major sites of ulceration and inflammation or one site of ulceration/inflammation, extending >1 cm along the length of the colon | 6–10 | If damage covers >2 cm along the length of the colon, the score is increased by one, for each additional centimeter of involvement |
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A lower score represents a healthier rat (modified from Peran et al., 2007 [11]).
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