TY - JOUR A2 - Correlo, Vitor M. AU - Bakirova, Ryszhan AU - Nukhuly, Altynbek AU - Iskineyeva, Ainara AU - Fazylov, Serik AU - Burkeyev, Meiram AU - Mustafayeva, Ayaulym AU - Minayeva, Yelena AU - Sarsenbekova, Akmaral PY - 2020 DA - 2020/08/18 TI - Obtaining and Investigation of the β-Cyclodextrin Inclusion Complex with Vitamin D3 Oil Solution SP - 6148939 VL - 2020 AB - Background. The research results of fat-soluble vitamin D3 (cholecalciferol) encapsulation with β-cyclodextrin have been presented in this work. The vitamin D3 inclusion complex with β-cyclodextrin was obtained under microwave radiation. The surface morphology of obtained clathrate inclusion complexes was described with the help of a scanning electron microscope. The thermographic measurement results on a differential scanning calorimeter have been presented. The activation energy of the β-cyclodextrin : vitamin D3 clathrate complex thermal oxidative destruction reaction was calculated. The clathrate thermal destruction kinetic parameters were determined. The inclusion complex spectral properties were characterized by IR-Fourier and 1H and 13C NMR spectroscopy. The existence of β-cyclodextrin inclusion complex with vitamin D3 in a 2 : 1 ratio was confirmed by the experimental results. The activation energy of thermal destruction of the inclusion complex of β-cyclodextrin with vitamin D3 was calculated using four different methods. SN - null UR - https://doi.org/10.1155/2020/6148939 DO - 10.1155/2020/6148939 JF - Scientifica PB - Hindawi KW - ER -