Asthma Control and Its Relationship with Obstructive Sleep Apnea (OSA) in Older Adults
Table 5
Univariate associations of severe asthma (step 3 or 4) with OSA (clinically-diagnosed and untreated) and other traditional factors of asthma control, in the older and younger asthma subjects.
Older ()
Younger ()
Odds ratio [95% confidence interval]
P value
Odds ratio [95% confidence interval]
P value
OSA
7.20 [2.02–25.74]
0.002
4.26 [2.19–8.28]
<0.0001
Age
1.04 [0.97–1.11]
0.30
1.01 [1.00–1.02]
0.12
Gender (female versus male)
0.97 [0.54–1.77]
0.93
1.35 [1.00–1.83]
0.05
BMI (categorized)
1.37 [0.95–1.98]
0.09
1.84 [1.54–2.20]
<0.0001
African-American (versus all others)
1.90 [0.48–7.55]
0.36
4.04 [2.14–7.60]
<0.0001
Rhinitis
0.43 [0.17–1.09]
0.08
0.27 [0.17–0.44]
<0.0001
Chronic sinusitis
0.67 [0.36–1.23]
0.20
0.93 [0.68–1.28]
0.67
Nasal polyps
0.92 [0.45–1.88]
0.82
1.35 [0.90–2.04]
0.15
GERD
1.94 [1.08–3.51]
0.03
1.64 [1.23–2.18]
0.0007
Psychiatric disease
1.26 [0.60–2.62]
0.54
1.50 [1.10–2.04]
0.01
Definition of abbreviations: OSA: obstructive sleep apnea; BMI: body mass index (kg/m2); GERD: gastroesophageal reflux disease.
