Asthma Control and Its Relationship with Obstructive Sleep Apnea (OSA) in Older Adults
Table 7
Multivariate associations of severe asthma (step 3 or 4) with OSA (clinically-diagnosed and untreated) and other traditional factors of asthma control, in the older and younger asthma subjects.
Older ()
Younger ()
Odds ratio [95% confidence interval]
P value
Odds ratio [95% confidence interval]
P value
OSA
6.67 [1.74–25.56]
0.006
2.61 [1.28–5.33]
0.008
Age
1.06 [0.98–1.14]
0.17
1.01 [0.99–1.02]
0.45
Gender (female versus male)
1.32 [0.61–2.86]
0.49
1.48 [1.03–2.11]
0.04
BMI (categorized)
1.06 [0.68–1.65]
0.81
1.49 [1.20–1.84]
0.0003
African-American (versus all others)
1.89 [0.27–13.24]
0.52
4.26 [1.89–9.59]
0.0005
Rhinitis
0.40 [0.12–1.28]
0.12
0.45 [0.25–0.81]
0.007
Chronic sinusitis
0.38 [0.16–0.91]
0.03
0.81 [0.54–1.22]
0.31
Nasal polyps
1.73 [0.60–4.96]
0.31
1.32 [0.78–2.23]
0.30
GERD
1.35 [0.67–2.71]
0.41
1.30 [0.91–1.85]
0.16
Psychiatric disease
1.68 [0.65–4.33]
0.28
1.05 [0.72–1.54]
0.81
Definition of abbreviations: OSA: obstructive sleep apnea; BMI: body mass index (kg/m2); GERD: gastroesophageal reflux disease.
