Complete Genome Sequence of Rothia mucilaginosa DY-18: A Clinical Isolate with Dense Meshwork-Like Structures from a Persistent Apical Periodontitis Lesion
Figure 3
(a) Domain architectures of two sigma factors on the genome of Rothia mucilaginosa DY-18. Existence of sigma-70 regions 1.2, 2, 3 and 4 in a sigma factor 7350 encoded by RMDY 18_07350 was predicted by the Pfam search, indicating a primary type sigma factor. Another sigma factor 7090 encoded by RMDY 18_07090 was predicted as an ECF-type sigma factor in which sigma-70 regions 2 and 4 were detected. Proteins are represented as thick horizontal lines and their domain structures are shown by filled rectangles. Numbers above the rectangles indicate the domain names (Sigma-70 regions 1.2, 2, 3, and 4). The line indicates 100 amino acids, and all the structures are to scale. (b) Genetic organization of the RMDY 18_07090 (7090) and flanking coding sequences. The RMDY 18_07090 is arranged in an operon-like structure with its cognate antisigma factor gene, RMDY 18_07080 (7080). Arrows indicate the coding sequences and their orientations. Two neighboring genes, RMDY 18_07100 (7100: lysophospholipase L1) and RMDY18_07070 (7070: 5-enolpyruvylshikimate-3-phosphate synthase), of this sigma-antisigma region were not regulators.
