Research Article
The Role of Endothelial Mesenchymal Transformation on Infantile Hemangioma
Table 2
The correlation between E-cadherin and N-cadherin expression and clinicopathologic characteristics in IHC analysis.
| Clinical indicators | Case (n) | E-cadherin expression | N-cadherin expression | + (%) | − (%) | | + (%) | − (%) | |
| Diagnostic category | Proliferation phase | 23 | 22 (95.7) | 1 (4.3) | <0.01 | 6 (26.1) | 17 (73.9) | <0.01 | Involution phase | 20 | 7 (35) | 13 (65) | | 20 (100.00) | 0 (0.00) | |
| Gender | Male | 19 | 13 (68.4) | 6 (31.6) | 0.903 | 13 (68.4) | 6 (31.6) | 0.342 | Female | 24 | 16 (66.7) | 8 (33.3) | | 13 (54.2) | 11 (45.8) | |
| Age (years old) | <1 | 22 | 21 (95.5) | 1 (4.5) | <0.01 | 6 (27.3) | 16 (72.7) | <0.01 | ≥1 | 21 | 8 (38.1) | 13 (61.9) | | 20 (95.2) | 1 (4.8) | |
| Depth (cm) | <0.5 | 20 | 14 (70.0) | 6 (30.0) | 0.739 | 14 (70.0) | 6 (30.0) | 0.954 | ≥0.5 | 23 | 15 (65.2) | 8 (34.8) | | 12 (52.2) | 11 (47.8) | |
| Size (cm2) | <4 | 21 | 15 (71.4) | 6 (28.6) | 0.586 | 12 (57.1) | 9 (42.9) | 0.663 | ≥4 | 22 | 14 (63.6) | 8 (36.4) | | 14 (63.6) | 8 (36.4) | |
| Classification | Mixed type | 12 | 9 (75) | 3 (25) | 0.639 | 6 (50.0) | 6 (50.0) | 0.428 | Superficial type | 22 | 15 (68.2) | 7 (31.8) | | 13 (59.1) | 9 (40.9) | | Deep type | 9 | 5 (55.6) | 4 (44.4) | | 7 (77.8) | 2 (22.2) | |
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values are obtained from χ2 test. |