Research Article

The Role of Endothelial Mesenchymal Transformation on Infantile Hemangioma

Table 2

The correlation between E-cadherin and N-cadherin expression and clinicopathologic characteristics in IHC analysis.

Clinical indicatorsCase (n)E-cadherin expressionN-cadherin expression
+ (%)− (%)+ (%)− (%)

Diagnostic category
Proliferation phase2322 (95.7)1 (4.3)<0.016 (26.1)17 (73.9)<0.01
Involution phase207 (35)13 (65)20 (100.00)0 (0.00)

Gender
Male1913 (68.4)6 (31.6)0.90313 (68.4)6 (31.6)0.342
Female2416 (66.7)8 (33.3)13 (54.2)11 (45.8)

Age (years old)
<12221 (95.5)1 (4.5)<0.016 (27.3)16 (72.7)<0.01
≥1218 (38.1)13 (61.9)20 (95.2)1 (4.8)

Depth (cm)
<0.52014 (70.0)6 (30.0)0.73914 (70.0)6 (30.0)0.954
≥0.52315 (65.2)8 (34.8)12 (52.2)11 (47.8)

Size (cm2)
<42115 (71.4)6 (28.6)0.58612 (57.1)9 (42.9)0.663
≥42214 (63.6)8 (36.4)14 (63.6)8 (36.4)

Classification
Mixed type129 (75)3 (25)0.6396 (50.0)6 (50.0)0.428
Superficial type2215 (68.2)7 (31.8)13 (59.1)9 (40.9)
Deep type95 (55.6)4 (44.4)7 (77.8)2 (22.2)

values are obtained from χ2 test.