Comparing Supervised Exercise Therapy to Invasive Measures in the Management of Symptomatic Peripheral Arterial Disease

Table 3

Supervised exercise versus endovascular revascularization.

Study	Follow-up	ABPI			MWD			ICD
		Baseline	Endpoint		Baseline	Endpoint		Baseline	Endpoint
Hobbs et al. [21]
EVR	6 months	0.69	0.93	0.013^†	185	698	0.008^†	84	698	0.011^†
SET		0.66	0.70	0.46^†	111	124	0.35^†	59	92	0.074^†
Mazari et al. [25]
EVR	12 months	0.71	0.90		77	146		31	75
SET		0.72	0.84	0.093	83	215	0.2	42	97	0.48
Spronk et al./Fakhry et al. [22–24]
EVR	7 years	0.63	0.84		174	1248		82	1022
SET		0.62	0.82	0.8	186	1168	0.48	104	804	0.15
Murphy et al. [18, 32]
EVR	18 months	0.7	0.7		5.2 min	8.4 min		1.8 min	4.8 min
SET		0.6	0.6	<0.001	5.6 min	10.6 min	0.16	1.8 min	5.1 min	0.77

ABPI: ankle brachial pressure index; MWD: maximal walk distance; ICD: intermittent claudication distance; EVR: endovascular revascularization; SET: supervised exercise therapy. Distances in metres unless otherwise stated. min represents time in minutes, claudication onset time/maximal walk time. value represents statistical comparison of interventions except in Hobbs et al. [21] where † represents change in measurement over study period.